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Needle infection occurred more frequently, Topiramate frequently it was changed (Table 4). But in some patients, the needle turned out to be infected after the first injection.

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A completely new, previously unseen side effect of insulin therapy, induced by new technologies for the production of insulin preparations, has become mass insulinophobia - the fear of treatment with certain insulin preparations, common among the general population.

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With a local lesion, the symptoms are characterized only in the area of topamax drug.